Prof. Dr. Masoud Fereidoni | Ferdowsi University oh Mashhad | Iran
Prof. Dr. Masoud Fereidoni is a distinguished expert in medical physiology, with a Ph.D. from Tarbiat Modares University, Tehran. He currently serves as an Assistant Professor in the Department of Biology at Ferdowsi University of Mashhad, where he has taught since 1995. His research spans neurophysiology, pain modulation, stress responses, and neuropharmacology, with a particular focus on morphine, G-protein signaling, and nociception. He has supervised numerous M.Sc. theses on experimental models of pain and memory, and has completed advanced training at international institutions, including Lund University (Sweden) and IBRO schools in Thailand and India.
Author Profile
Early Academic Pursuits
Prof. Dr. Masoud Fereidoni began his academic journey with a B.Sc. in Biology from Ferdowsi University of Mashhad in 1987. His passion for understanding physiological mechanisms led him to pursue a M.Sc. in Animal Physiology at Shaheed Beheshti University in Tehran, graduating in 1996. Building on his foundational knowledge, he achieved his Ph.D. in Medical Physiology from Tarbiat Modares University in 2007. His academic journey was shaped by a consistent focus on neurophysiology and pain modulation, with early research centered on the antinociceptive and anti-inflammatory effects of medicinal plants.
Professional Endeavors
Prof. Dr. Fereidoni's career reflects a trajectory of steady academic and research progression. Starting as a laboratory technician for vaccine production at the Razi Institute (1990–1992), he moved into academia as an instructor and later a lecturer at Ferdowsi University of Mashhad from 1992–2007. Since 2007, he has served as an assistant professor in the Department of Biology at Ferdowsi University. Over the years, he has participated in and conducted numerous specialized training courses and international workshops, including those on electrophysiology, neuroimaging, patch clamp techniques, and animal cell culture, with a sabbatical at the Neuronano Research Center, Lund University, Sweden in 2009.
Contributions and Research Focus
Prof. Dr. Fereidoni has made significant contributions in the fields of pain modulation, stress physiology, and neuropharmacology. His Ph.D. thesis explored the interaction of G-protein signaling and morphine-induced analgesia/hyperalgesia under stress conditions, offering insights into spinal cord physiology. His post-graduate thesis supervision reflects a broad research spectrum, including nociception, morphine effects, neurotransmitter systems, stress physiology, neurodevelopment, and toxicology using Drosophila melanogaster. More recently, his studies have expanded toward novel applications such as wound healing and cognitive enhancement, areas where nanoparticles are increasingly becoming relevant. His interdisciplinary approach positions nanoparticles as a future research direction in neurophysiological modulation, targeted drug delivery, and regenerative medicine.
Impact and Influence
Dr. Fereidoni has significantly influenced both the academic and applied fields of physiology and neuroscience in Iran. His multidisciplinary research, combining pharmacology, behavioral neuroscience, and toxicology, has equipped graduate students with holistic scientific training. His affiliations with the Iranian Society of Biology and the Iranian Society of Physiology & Pharmacology demonstrate his commitment to national scientific development. His international exposure, particularly through IBRO schools and sabbaticals, has amplified his academic reach and promoted knowledge exchange. His work has laid the groundwork for the integration of nanoparticles in future neurophysiological research paradigms.
Academic Cites
Prof. Dr. Fereidoni’s scholarly work has contributed to a growing body of literature in medical physiology, with his research being cited in areas such as stress-induced neural modulation, opioid pharmacology, and environmental neurotoxicology. His collaborative and thesis-based outputs reflect substantial academic interest, particularly in understanding mechanisms underlying pain and memory. With the ongoing global shift toward nanoparticles in biomedical research, his foundational work on drug delivery, neuroinflammation, and electrophysiological modulation is expected to gain even broader recognition.
Legacy and Future Contributions
Prof. Dr. Masoud Fereidoni is recognized not only for his academic achievements but also for his role in mentoring emerging scientists. His guidance in over 25 postgraduate theses shows his commitment to student development and scientific curiosity. His future contributions are likely to focus on the incorporation of nanoparticles into neuropharmacology and regenerative neuroscience, areas he has already indirectly influenced through his research on stress, learning, and drug modulation. His legacy is rooted in both education and innovation, laying a strong foundation for translational research in neuroscience and physiology.
Nanoparticles
Prof. Dr. Fereidoni's research intersects meaningfully with the emerging applications of nanoparticles, especially in pain modulation and wound healing. With evolving interest in using nanoparticles for targeted drug delivery, his work on morphine, inflammation, and neurophysiology sets a solid base for integration of nanoparticles in future therapeutic models. His interdisciplinary expertise continues to enrich the evolving domain of biomedical applications in physiology.
Notable Publications
Chronic forced swim stress inhibits ultra-low dose morphine-induced hyperalgesia in rats
- Authors: M. Fereidoni, M. Javan, S. Semnanian, A. Ahmadiani
Journal: Behavioural Pharmacology
Year: 2007
Citations: 31
Pharmacological upregulation of GLT-1 alleviates the cognitive impairments in the animal model of temporal lobe epilepsy
- Authors: D. Ramandi, M. Elahdadi Salmani, A. Moghimi, T. Lashkarbolouki, et al.
Journal: PLoS One
Year: 2021
Citations: 27
The effect of intracerebroventricular administration of orexin receptor type 2 antagonist on pentylenetetrazol-induced kindled seizures and anxiety in rats
- Authors: S. Asadi, A. Roohbakhsh, A. Shamsizadeh, M. Fereidoni, E. Kordijaz, et al.
Journal: BMC Neuroscience
Year: 2018
Citations: 25
Celecoxib, indomethacin, and ibuprofen prevent 6-hydroxydopamine-induced PC12 cell death through the inhibition of NFκB and SAPK/JNK pathways
- Authors: E. Ramazani, Z. Tayarani-Najaran, M. Fereidoni
Journal: Iranian Journal of Basic Medical Sciences
Year: 2019
Citations: 24
Use of stem cells in the regeneration of peripheral nerve injuries: an overview
- Authors: M.B. Ghayour, A. Abdolmaleki, M. Fereidoni
Journal: The Neuroscience Journal of Shefaye Khatam
Year: 2015
Citations: 21